Structure-Function Relationship of Vitamin D.
نویسندگان
چکیده
منابع مشابه
Relationship of structure and function of DNA-binding domain in vitamin D receptor.
While the structure of the DNA-binding domain (DBD) of the vitamin D receptor (VDR) has been determined in great detail, the roles of its domains and how to bind the motif of its target genes are still under debate. The VDR DBD consists of two zinc finger modules and a C-terminal extension (CTE), at the end of the C-terminal of each structure presenting α-helix. For the first zinc finger struct...
متن کاملVitamin D & endothelial function
There is increasing interest in the extra-skeletal roles of vitamin D for health and well-being. Poor vitamin D status has been associated with obesity, cardiovascular disease, type 2 diabetes and mental health. Endothelial dysfunction may underscore insulin resistance and hence predispose to both cardiovascular disease (CVD) and type 2 diabetes. The objective of this review was to gain an appr...
متن کاملRelationship of Vitamin D and Respiratory Diseases
1Institute of Metabolic Disease Research and Drug Development, China Medical University, Shenyang, Liaoning Province 110122, PR China 2Department of Medicine, Division of Biological Sciences, University of Chicago, Chicago IL 60637, USA *Corresponding author Hongguang Nie, MD, PhD Professor Institute of Metabolic Disease Research and Drug Development China Medical University No.77 Puhe Road She...
متن کاملVitamin D and Immune Function
Vitamin D metabolizing enzymes and vitamin D receptors are present in many cell types including various immune cells such as antigen-presenting-cells, T cells, B cells and monocytes. In vitro data show that, in addition to modulating innate immune cells, vitamin D also promotes a more tolerogenic immunological status. In vivo data from animals and from human vitamin D supplementation studies ha...
متن کاملVitamin D and neurocognitive function
In recent years, emerging evidence has linked vitamin D not only to its known effects on calcium and bone metabolism, but also to many chronic illnesses involving neurocognitive decline. The importance of vitamin D3 in reducing the risk of these diseases continues to increase due to the fact that an increasing portion of the population in developed countries has a significant vitamin D deficien...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1996
ISSN: 1341-8327,1884-1996
DOI: 10.5650/jos1996.45.415